Caredermis

reaction mass of 3-(difluoromethyl)-1-methyl-n-[(1rs,4sr,9rs)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and 3-(difluoromethyl)-1-methyl-n-[(1rs,4sr,9sr)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide [≥ 78 % syn isomers ≤ 15 % anti isomers relative content]; isopyrazam

Severity 10/10

cosmetic ingredient

Is reaction mass of 3-(difluoromethyl)-1-methyl-n-[(1rs,4sr,9rs)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and 3-(difluoromethyl)-1-methyl-n-[(1rs,4sr,9sr)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide [≥ 78 % syn isomers ≤ 15 % anti isomers relative content]; isopyrazam safe?

reaction mass of 3-(difluoromethyl)-1-methyl-n-[(1rs,4sr,9rs)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and 3-(difluoromethyl)-1-methyl-n-[(1rs,4sr,9sr)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide [≥ 78 % syn isomers ≤ 15 % anti isomers relative content]; isopyrazam carries significant published concerns (cancer concern, hormone disruption, allergy risk, environmental impact).

Documented concerns

Cancer concern

10/10

Classified by EU CLP Carc. 2.

Hormone disruption

10/10

Classified by EU CLP Repr. 1B.

Allergy risk

10/10

Classified by EU CLP Skin Sens. 1B.

Environmental impact

10/10

Classified by EU CLP Aquatic Acute 1/Aquatic Chronic 1.

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